This gene mutation is key to glioblastoma’s ‘immortality’ and could point to drug targets
May 09, 2019 The mutation, which occurs in a gene regulator called TERT and is the most common mutation in glioblastoma, gives cancer cells “immortality,” or the ability to divide and spread indefinitely. By studying cells from glioblastoma patients, the UCSF researchers discovered that a particular form of a protein called GABP drives TERT promoter … Read more