Lori A Carr January 14, 2020 After examining the mechanisms of 10 cancer drugs that were thought to target one of six (6) proteins, Jason Sheltzer and colleagues at CSHL made the unexpected discovery that the drugs may indeed kill tumor cells, but not by blocking their intended targets. The medicines they scrutinized came from companies that included Celgene … Read more
January 09, 2020 Conducted in partnership with academic and healthcare institutions, the studies aim to tap nearly any Apple product customer as a potential research participant. The tech giant’s planed to make its Research app available as a free download in late 2019. Apple’s previous heart-focused study canvassed more than 400,000 people in the U.S. … Read more
January 07, 2020 Why the surge in oncology successes? Because pharmaceutical companies have taken a new approach to drug development, focusing on pursuing novel mechanisms for treating cancer and validating them with clinical trials that are much better designed than they were in the past. Couple that with an FDA that has doubled down on … Read more
January 02, 2020 When the researchers inhibited FABP4 in white adipose tissue — commonly known as the unhealthy white fat—they observed a reduction in lipid storage. Then they tried it in mice that had been fed a high-fat diet, injecting them twice a week with the CRISPR interference system. The mice lost 20% of their … Read more
December 31, 2019 After one (1) year, 14 out of the 16 treated lesions tested negative for signs of cancer, according to procedure developer Nanospectra Biosciences. The company’s gold-silica particles, dubbed AuroShells, are designed to absorb wavelengths of light that approach the infrared spectrum and are still able to pass through tissue. When charged up … Read more
December 26, 2019 The FDA named several models from Olympus, Fujifilm and Pentax as ones to avoid in the future, all designed with fixed, rigid end caps. These can contain tight crevices that can be difficult to fully clean and may harbor potentially dangerous infections between uses. Instead, the FDA is urging duodenoscopes be designed … Read more
December 24, 2019 Currently being developed under the BRAIN Initiative of the National Institutes of Health (NIH), the OBServ system includes glasses that not only film the scene in front of a person but also track their eye movement to see where they are focusing their gaze. Though AMD is a leading cause of blindness … Read more
December 19, 2019 “Concussion is a three-legged stool. When you get assessed, you get assessed for eye movement — ‘follow the tip of my finger’ — and you get assessed for cognitive and memory issues. You also get assessed for balance,” said Melissa Hunfalvay, co-founder and Chief Science Officer at RightEye, a company that markets … Read more
December 17, 2019 The team used single-nucleus RNA sequencing to classify neuronal cells in a region of human cortex that plays a key role in many cognitive functions. The 75 distinct cell types identified are similar to cells in the mouse brain; however, there are also some crucial differences, the researchers reported in a study published … Read more
December 15, 2019 They isolated the toxin from the venom of the Australian black rock scorpion and dubbed it WaTx (wasabi receptor toxin). The researchers probed the toxin and discovered that it triggers TRPA1 by forcing its way into nerve cells. That makes it different from most compounds, which have to endure much more complex … Read more