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Researchers ask if SARS-CoV-2, cancers could be linked: National data and some large cancer treatment organizations have indicated an unexpected rise in aggressive, late-stage cancers since the COVID-19 pandemic began. Some experts believe the trend is due to health care disruptions caused by the crisis; however, David Tuveson of the Cancer Center at Cold Spring Harbor Laboratory said some small early studies suggest the viral infection can lead to inflammation and other responses that may factor into the growth of cancer cells.

New compound demonstrates reversible male contraception in mice: A new hormone-independent male contraceptive called compound CDD-2807 demonstrated reversible contraceptive action in mice, with reductions in sperm count and motility through inhibition of STK33, a protein known to be involved in infertility, according to a study in Science. Researchers plan to test this contraceptive in non-human primates as a next step, with the hope of providing more options for male birth control.

POMC (pro-opiomelanocortin) gene mutations linked to obesity in dogs: Researchers have found that mutations in the POMC gene lead to increased body fat in dogs, as a result of increased appetite and persistence during the “sausage-in-a-box test” and reduced resting metabolic rates. Eleanor Raffan, Senior Author of the study in Science Advances, hopes this work can be used to improve canine health and provide clues for understanding human obesity genetics.

Mice show infection after drinking H5N1-contamination raw milk: Lab mice that consumed 20 drops of raw milk from cows infected with H5N1 avian influenza developed ruffled fur and lethargy on the first day; high viral loads were found in the animals’ nasal passages, trachea and lungs; lower levels of virus were found in their other organs; and the virus was found in the mammary glands of two mice that were not lactating, researchers reported in The New England Journal of Medicine. Virus levels remained high in contaminated milk that was refrigerated for five (5) weeks; heating milk to 145 degrees F killed the virus in five (5) minutes; however, heating to 161.6 degrees F for 20 seconds killed some but not all of the virus.

Scientists find microplastics in testicular tissue: University of New Mexico toxicologist John Yu and colleagues have discovered microplastics in the testicles of humans and dogs, raising concerns about potential effects on male fertility, according to a study in Toxicological Sciences. The study detected plastics such as polyethylene and polyvinyl chloride in the samples tested — an unexpected finding given the tight blood-tissue barrier in testicles, Yu said — and the results underscore the importance of further research into how microplastics affect human health.

Rocketing tumors into space illuminates human biology: Hematologist Catriona Jamieson, Director of the Sanford Stem Cell Institute, says that sending tumor organoids and stem cells aboard space flights is helping her understand stem cell aging and the mechanisms behind cancer growth. The tumors grew very rapidly, and Jamieson’s Lab Manager, Jessica Pham, suggested testing a novel blocker that appears to work as a cancer kill-switch.

First fetus-to-fetus kidney tissue transplant with rats successful: In a “first of its kind” project, surgeons in Japan transplanted kidney tissue from one rat fetus to another that was still in the womb, said Study Leader Takashi Yokoo, a Nephrologist at Jikei University School of Medicine in Tokyo. The advancement is a step toward the transplantation of fetal pig kidneys into human fetuses.

Bees vaccinated against bacterial disease resist virus: Honeybee hives vaccinated against American foulbrood diseases were more resistant to a virus carried by varroa mites than unvaccinated hives despite having an equivalent number of mites, veterinarian Nigel Swift of Dalan Animal Health reported at the World Vaccine Congress. The vaccine, made by Dalan, might boost honeybees’ immune systems, Dr. Swift says.

Menopause – the unspoken challenge for female workers: For women between the ages of 40 and 58, balancing the effects of menopause with the demands of their jobs is daunting, with financial losses put at $1.8 billion, and sometimes impossible, with about a quarter of women in one survey saying they were considering leaving their jobs. Bristol Myers Squibb, Adobe, and Bank of America are among the few companies that offer menopause benefits, and grassroots campaigns like Menopause Mandate and Let’s Talk Menopause raise awareness about the issue.

Can contraceptives prevent NYC rat overpopulation? The New York City Council is considering a proposal to try distributing rat contraceptives as a humane way to control the city’s rat population without the use of chemicals that harm nontarget species. The proposed pilot test would involve distributing male and female contraceptives encased in salty, fatty pellets in rat-infested areas.