Subtle chemical shift reverses pre-diabetes in Merck-partnered mouse trial
October 17, 2019 Summers’ team collaborated with scientists at Merck Research Laboratories to develop a technique for lowering the amount of ceramides in the body. They accomplished that by shutting down an enzyme called dihydroceramide desaturase 1 (DES1). That, in turn, shifted two hydrogen atoms from ceramide, crippling the fatty lipid. When the researchers made … Read more