Scorpion toxin uncovers insights into pain that could inspire non-opioid treatments

December 15, 2019 They isolated the toxin from the venom of the Australian black rock scorpion and dubbed it WaTx (wasabi receptor toxin).  The researchers probed the toxin and discovered that it triggers TRPA1 by forcing its way into nerve cells.  That makes it different from most compounds, which have to endure much more complex … Read more

Zoleka Mandela Joins Global Access To Cancer Care Foundation

December 10, 2019 As a GACCF Ambassador, Mandela will use her voice to advocate for GACCF’s work in low and middle-income countries (LMICs).  She will also educate the public about GACCF’s mission to educate physicians and medical specialists who work in the field of oncology and highlight the foundation’s role in treating cancer in these … Read more

The first 3D models of Parkinson’s, MS are headed into space

December 05, 2019 The disease models comprise microglia — the immune cells of the brain — as well as neurons.  They are the work of a collaboration between researchers at Aspen Neuroscience in La Jolla, California, the New York Stem Cell Foundation Research Institute and San Diego-based Summit for Stem Cell.  The team created them … Read more

CVS moves into kidney care with clinical trial for home dialysis device

December 03, 2019 The clinical trial of the company’s HemoCare Hemodialysis System for the administration of home hemodialysis will involve up to 70 patients at 10 sites, CVS said.  Home hemodialysis helps facilitate longer, more frequent dialysis treatments compared to in-center treatments, according to the company.  CVS officials said the clinical trial for the home dialysis … Read more

Pharmacies take up drug disposal effort Big Pharma has fought

November 28, 2019 More than 550 medication disposal units across the country nation are now searchable on Google Maps using a computer or mobile device, Rite Aid announced in July.  Users can type or say “medication disposal near me,” and the software will show the closest locations.  “We are constantly looking for additional ways to … Read more

Reversing the risk of sudden cardiac death with gene therapy

November 21, 2019 In two (2) studies published in the journal Circulation, scientists at Boston Children’s built what could be the first human tissue model of catecholaminergic polymorphic ventricular tachycardia (CPVT), a potentially lethal form of arrhythmia that’s triggered by exercise or sudden emotional stress.  Using that model, they developed a gene therapy procedure that … Read more

The ‘hunger hormone’ shows potential in promoting memory

November 19, 2019 After the researchers blocked ghrelin signaling in rats, they observed that the animals showed signs of impaired memory, they reported at the annual meeting of the Society for the Study of Ingestive Behavior.  That led the USC team to hypothesize that ghrelin may also help control memory. Ghrelin is produced mainly in the … Read more

FDA contributes to hunt for new heart failure endpoints

November 14, 2019 Working as part of the Yale University-Mayo Clinic Center of Excellence in Regulatory Science and Innovation (CERSI), the FDA has identified the need for alternative heart failure endpoints.  Improving mortality and reducing hospitalizations are gold-standard endpoints for clinical trials; however, attempts to demonstrate the efficacy of drugs against those yardsticks are confounded … Read more

With test, Merck takes temperature-controlled drug delivery by drone from remote idea to remote locations

November 13, 2019 Merck initiated the idea, and a collection of players coordinated by humanitarian aid organization Direct Relief have now moved to proof-of-concept missions.  They developed and flew a drone with a temperature-controlled payload over the waters around the Bahamas.  “This successful pilot demonstrates the potential of innovative unmanned aerial vehicles technology to aid … Read more